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AKA-213
Ipidacrine Hydrochloride Hydrate
Cat. No.
AKA-213
CAS No.
118499-70-0
MF
C12H19ClN2O
MW
242.75
Ipidacrine hydrochloride is an active and brain-penetrant acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitor. It also acts as a partial agonist of M2-cholinergic receptors and exhibits reversible cholinesterase inhibition.
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Technical Data
Description
Storage and Shipping
References
Product Name
Ipidacrine Hydrochloride Hydrate
CAS No.
118499-70-0
MF
C12H19ClN2O
MW
242.75
Specification
97%
Research Area
Cognitive impairment
Description
Ipidacrine hydrochloride is an active and brain-penetrant acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitor. It also acts as a partial agonist of M2-cholinergic receptors and exhibits reversible cholinesterase inhibition. Packing: 1kg/bag; 25kg/drum or as request Availability: In stock
Documents
Certificate of Analysis (COA), API specification, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Kojima J, Onodera K, Ozeki M, et al. Ipidacrine (NIK-247): A review of multiple mechanisms as an antidementia agent. CNS Drug Reviews. 1998;4(3):247-259.
[2]. Burov Y, Cadysheva L, Rodakidze T, et al. Pharmacological effects of amiridin. European Journal of Pharmacology. 1990;183:1464.
[3]. Bykov V, Gushchina E, Morozov S, et al. Ipidacrine (Axamon), a reversible cholinesterase inhibitor, improves erectile function in male rats with diabetes mellitus-induced erectile dysfunction. Sexual Medicine. 2022;10(1):100477.
[4]. NCATS Inxight Drugs. Ipidacrine hydrochloride monohydrate[EB/OL].
[5]. Onodera K, Kojima J, Wachi M. Ipidacrine (NIK-247), a novel antidementia, rapidly enters the brain and improves scopolamine-induced amnesia in rats during the Morris water maze task. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 1998;18(2):33-37.
[2]. Burov Y, Cadysheva L, Rodakidze T, et al. Pharmacological effects of amiridin. European Journal of Pharmacology. 1990;183:1464.
[3]. Bykov V, Gushchina E, Morozov S, et al. Ipidacrine (Axamon), a reversible cholinesterase inhibitor, improves erectile function in male rats with diabetes mellitus-induced erectile dysfunction. Sexual Medicine. 2022;10(1):100477.
[4]. NCATS Inxight Drugs. Ipidacrine hydrochloride monohydrate[EB/OL].
[5]. Onodera K, Kojima J, Wachi M. Ipidacrine (NIK-247), a novel antidementia, rapidly enters the brain and improves scopolamine-induced amnesia in rats during the Morris water maze task. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 1998;18(2):33-37.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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